Brain aging? It depends on the slowdown in brain protein synthesis

This was revealed in an international study coordinated by the Scuola Normale Superiore, the Leibniz Institute for Ageing Research in Jena, and Stanford University, published in the prestigious journal Science. This study was conducted by an international team coordinated by the Scuola Normale Superiore with the Bio@SNS Laboratory, the Leibniz Institute for Aging Research, and […]

Genetics of “long Covid” revealed. The study published in the journal Nature Genetics

Published in Nature Genetics is the international study that has for the first time identified new genetic variants associated with the risk of developing the syndrome, known to cause chronic fatigue, cognitive and respiratory difficulties, and muscle pain. Italy contributed scholars from the University of Milan, the University of Siena, and the Institute of Biomedical […]

CellHit: a web server to predict and analyze drug responsiveness of cancer patients

Francesco Carli and Francesco Raimondi, researchers at the Bio@SNS Biology Laboratory, Scuola Normale Superiore di Pisa, are part of the research team that has developed the CellHit web server, a web-based platform designed to predict and analyze cancer patients’ drug responsiveness using transcriptomic data. CellHit provides precomputed predictions on TCGA samples and offers the ability […]

THE on Wired: the hidden intelligence of our gut, a silent dialogue with the brain

Wired Italy takes us into the heart of a study by THE Tuscany Health Ecosystem, with Prof. Tommaso Pizzorusso and Paola Tognini, revealing how the microbiota affects mood, cognitive function and even seizures. In CDKL5-KO mice, early gut dysbiosis coincides with seizure onset.Intervening with antibiotics and healthy microbiota transplants realigns neuronal responses and dramatically reduces […]

Imbalances in the gut microbiota are the cause of some neurodevelopmental disorders

The study, published in the journal Cell Reports, is a collaboration between Scuola Sant’Anna with the interdisciplinary Health Science Center, Scuola Normale Superiore with the Biology Laboratory, the University of Pisa, CNR and the Max Planck Institute in Berlin. CDKL5 Deficiency Disorder (CDD) is a rare and severe genetic disease that predominantly affects girls, causing […]