Brain aging? It depends on the slowdown in brain protein synthesis

This was revealed in an international study coordinated by the Scuola Normale Superiore, the Leibniz Institute for Ageing Research in Jena, and Stanford University, published in the prestigious journal Science.

This study was conducted by an international team coordinated by the Scuola Normale Superiore with the Bio@SNS Laboratory, the Leibniz Institute for Aging Research, and Stanford University, in collaboration with the Anton Dohrn Zoological Station in Naples and the University of Trieste, and published in the prestigious journal Science. The study is entitled “Altered translation elongation contributes to key hallmarks of aging in the killifish brain.”

The results were obtained by observing the brain aging process in Nothobranchius furzeri (turquoise killifish), a small annual fish from East Africa known for its very short lifespan in captivity (less than a year). Alessandro Cellerino (pictured), professor of physiology at the Scuola Normale and one of the study’s coordinators, had the intuition to introduce it as a new model for the study of aging more than twenty years ago in Pisa.